Anticorps Polyclonal de lapin anti-ALDH1L2

• Phare
• Validé par KD/KO

ALDH1L2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21391-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 21391-1-AP (same clone as 21391-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21391-1-AP (ALDH1L2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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  WB analysis using 21391-1-AP (same clone as 21391-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21391-1-AP (ALDH1L2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 21391-1-AP (same clone as 21391-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas slide using 21391-1-AP (ALDH1L2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 21391-1-AP (same clone as 21391-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas slide using 21391-1-AP (ALDH1L2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 21391-1-AP (same clone as 21391-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart slide using 21391-1-AP (ALDH1L2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 21391-1-AP (same clone as 21391-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart slide using 21391-1-AP (ALDH1L2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 21391-1-AP (same clone as 21391-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using ALDH1L2 antibody (21391-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21391-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21391-1-PBS cible ALDH1L2 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ALDH1L2 Protéine recombinante Ag16046
• Nom complet: aldehyde dehydrogenase 1 family, member L2
• Masse moléculaire calculée: 923 aa, 102 kDa
• Poids moléculaire observé: 102 kDa, 89 kDa
• Numéro d’acquisition GenBank: BC103935
• Symbole du gène: ALDH1L2
• Identification du gène (NCBI): 160428
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ALDH1L2(Aldehyde dehydrogenase family 1 member L2) is also named as mitochondrial 10-FTHFDH, mtFDH and belongs to the aldehyde dehydrogenase family and ALDH1L subfamily. The ALDH1L2 gene has three transcriptional variants with the molecular weight of 102 kDa, 42 kDa and 89 kDa(PMID:19823103). It is a mitochondrial enzyme, a likely source of CO2 production from 10-formyltetrahydrofolate in mitochondria and playing an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell(PMID: 20498374). It also has dehydrogenase/hydrolase activities similar to cytosolic FDH (ALDH1L1). The native ALDH1L2 has been reported to exist as a dimer or tetramer(PMID:7822273).

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