Anticorps Monoclonal anti-ALDH2

• Phare
• Validé par KD/KO

ALDH2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2G10F4

N° de cat : 68237-1-PBS

Synonymes

ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM

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Galerie de données de validation

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  WB analysis of mouse liver using 68237-1-Ig (same clone as 68237-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of pig liver using 68237-1-Ig (same clone as 68237-1-PBS)

  pig liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 68237-1-Ig (same clone as 68237-1-PBS)

  WB result of ALDH2 antibody (68237-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ALDH2 transfected HepG2 cells. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rabbit liver using 68237-1-Ig (same clone as 68237-1-PBS)

  rabbit liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat liver using 68237-1-Ig (same clone as 68237-1-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68237-1-PBS cible ALDH2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: ALDH2 Protéine recombinante Ag7463
• Nom complet: aldehyde dehydrogenase 2 family (mitochondrial)
• Masse moléculaire calculée: 56 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC002967
• Symbole du gène: ALDH2
• Identification du gène (NCBI): 217
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.

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