Anticorps Recombinant de lapin anti-Angiogenin

Angiogenin Recombinant Antibody for WB, IF/ICC, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242738D1

N° de cat : 85635-1-PBS

Synonymes

ANG, ANG 1, ANG I, ANG1, ANGI

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Galerie de données de validation

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  WB analysis using 85635-1-RR (same clone as 85635-1-PBS)

  Untreated and Brefeldin A treated HepG2 cells were subjected to SDS PAGE followed by western blot with 85635-1-RR (ANG antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85635-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 85635-1-RR (same clone as 85635-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using ANG antibody (85635-1-RR, Clone: 242738D1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85635-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85635-1-PBS cible Angiogenin dans les applications de WB, IF/ICC, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Angiogenin Protéine recombinante Eg1930
• Nom complet: angiogenin, ribonuclease, RNase A family, 5
• Masse moléculaire calculée: 147 aa, 17 kDa
• Poids moléculaire observé: 14 kDa
• Numéro d’acquisition GenBank: BC054880
• Symbole du gène: Angiogenin
• Identification du gène (NCBI): 283
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Angiogenin (ANG), an angiogenic ribonuclease, is a member of the vertebrate-specific, secreted RNASE superfamily. Angiogenin, originally identified as a tumor angiogenic factor, was related with the growth and metastasis of numerous tumors. Angiogenin has been proposed as a permissive factor for angiogenesis induced by other angiogenic factors, including vascular endothelial growth factor (VEGF), basic fibroblast growth factor, acidic fibroblast growth factor, and epidermal growth factor. Angiogenin production and secretion may be stimulated by hypoxia. Increased angiogenin serum levels have been associated with the incidence and severity of several human tumors, including HCC. It is a 17 kDa precursor which is cleaved to generate the 14 kDa mature protein.

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