Anticorps Polyclonal de lapin anti-ANKRD18A

ANKRD18A Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24087-1-PBS

Synonymes

ankyrin repeat domain 18A, KIAA2015

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Galerie de données de validation

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  IHC staining of mouse liver using 24087-1-AP (same clone as 24087-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 24087-1-AP (ANKRD18A antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24087-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24087-1-AP (same clone as 24087-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24087-1-AP (ANKRD18A antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24087-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24087-1-PBS cible ANKRD18A dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ANKRD18A Protéine recombinante Ag21335
• Nom complet: ankyrin repeat domain 18A
• Masse moléculaire calculée: 992 aa, 116 kDa
• Numéro d’acquisition GenBank: BC152434
• Symbole du gène: ANKRD18A
• Identification du gène (NCBI): 253650
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ANKRD18A is an ankyrin repeat-containing protein that likely operates in the realm of epigenetic regulation, potentially influencing gene expression via DNA methylation mechanisms. Although its exact biochemical roles remain unclear, its frequent promoter hypermethylation in lung cancer, along with germline variation in vulvar skin disorders, underscores a compelling link to disease pathogenesis. Located on chromosome 9p13.1, ANKRD18A remains a compelling subject for further functional and clinical exploration.

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