Anticorps Polyclonal de lapin anti-AP3S1

AP3S1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32945-1-PBS

Synonymes

Adaptor-related protein complex 3 subunit sigma-1, AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, CLAPS3, Clathrin-associated/assembly/adaptor protein, small 3

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Galerie de données de validation

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  WB analysis using 32945-1-AP (same clone as 32945-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32945-1-AP (AP3S1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32945-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32945-1-PBS cible AP3S1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AP3S1 Protéine recombinante Ag37523
• Nom complet: adaptor-related protein complex 3, sigma 1 subunit
• Masse moléculaire calculée: 22 kDa
• Poids moléculaire observé: 22 kDa
• Numéro d’acquisition GenBank: BC000804
• Symbole du gène: AP3S1
• Identification du gène (NCBI): 1176
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AP-3 complex subunit sigma-1 (AP3S1) is a component of the heterotetrameric adaptor protein complex-3 (AP-3), which plays a central role in intracellular protein trafficking (PMID: 34565296). AP3S1 is also a potential pan-cancer oncogene and plays an essential role in tumorigenesis and cancer immunity. Elevated expression of AP3S1 indicates an immunosuppressive microenvironment and can be used as a potential prognostic biomarker and a target for immunotherapy (PMID: 35874816; 38609993).

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