Anticorps Polyclonal de lapin anti-AP4B1

AP4B1 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16313-1-PBS

Synonymes

Beta4-adaptin, Beta subunit of AP-4, AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1

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Galerie de données de validation

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  WB analysis using 16313-1-AP (same clone as 16313-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16313-1-AP (AP4B1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16313-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 16313-1-AP (same clone as 16313-1-PBS)

  IP result of anti-AP4B1 (IP:16313-1-AP, 4ug; Detection:16313-1-AP 1:300) with HeLa cells lysate 3200ug. This data was developed using the same antibody clone with 16313-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16313-1-PBS cible AP4B1 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AP4B1 Protéine recombinante Ag9348
• Nom complet: adaptor-related protein complex 4, beta 1 subunit
• Masse moléculaire calculée: 739 aa, 83 kDa
• Poids moléculaire observé: 75-83 kDa
• Numéro d’acquisition GenBank: BC014146
• Symbole du gène: AP4B1
• Identification du gène (NCBI): 10717
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Adaptor protein (AP) complex is a component of intracellular protein transport. The AP4 complex is involved in sorting transmembrane cargo proteins into transport vesicles for trans-Golgi network export. AP4B1 is a member of the AP4 complex, which also includes AP4E1, AP4M1 and AP4S1. Loss-of-function variants in any of these four members can lead to AP-4-associated hereditary spastic paraplegia (HSP), a neurodegenerative disorder (PMID: 30543385). This antibody recognizes AP4B1.

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