Anticorps Monoclonal anti-APBB1

APBB1 Monoclonal Antibody for IF-P

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat, souris

Applications

IF-P

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

1B9G10

N° de cat : CL594-67077

Synonymes

APBB1, FE65, Protein Fe65, RIR

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Galerie de données de validation

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  IF Staining of mouse brain using CL594-67077

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite®594 APBB1 antibody (CL594-67077, Clone: 1B9G10 ) at dilution of 1:200.

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  IF Staining of mouse brain using CL594-67077

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite®594 APBB1 antibody (CL594-67077, Clone: 1B9G10 ) at dilution of 1:200.

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Applications testées

• Résultats positifs en IF-P: tissu cérébral de souris,

Dilution recommandée

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-67077 cible APBB1 dans les applications de IF-P et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: APBB1 Protéine recombinante Ag27436
• Nom complet: amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
• Masse moléculaire calculée: 708 aa, 77 kDa
• Numéro d’acquisition GenBank: BC010854
• Symbole du gène: APBB1
• Identification du gène (NCBI): 322
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Conditions de stockage: Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

APBB1(Amyloid-beta A4 precursor protein-binding family B member 1) encoded FE65 protein. It was known as a binding partner of APP in the Alzheimer's disease studies, and expressed at high levels in brain especially in cerebellum, hippocampus, and cortex. FE65 and FE65-like (FE65L or FE65L1) proteins are cytoplasmic adaptor proteins that possess two phosphotyrosine binding domains (PTB1 and PTB2) and one WW binding domain (PMID:22429478). After phosphorylation modification, the band of FE65 protein would appear around 100 kDa. However, some tested a non-specific band at 55-60 kDa, it was refer to as FE65-like protein(PMID:12843239).

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