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Anticorps Polyclonal de lapin anti-APOB48R

APOB48R Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25328-1-PBS

Synonymes

apoB 48R, apoB-48R, APOBR, Apolipoprotein B 100 receptor, Apolipoprotein B 48 receptor

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using APOB48R Polyclonal antibody (25328-1-AP)

    WB analysis using 25328-1-AP (same clone as 25328-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25328-1-AP (APOB48R antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25328-1-PBS in a different storage buffer formulation.

Informations sur le produit

25328-1-PBS cible APOB48R dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène APOB48R Protéine recombinante Ag18204
Nom complet apolipoprotein B48 receptor
Masse moléculaire calculée 1088 aa, 116 kDa
Poids moléculaire observé116 kDa
Numéro d’acquisition GenBankBC119786
Symbole du gène APOB48R
Identification du gène (NCBI) 55911
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Apolipoprotein B48 receptor (APOB48R) is a macrophage receptor that binds to apoB of dietary triglyceride-rich lipoproteins or to a similar apoB-like domain in hypertriglyceridemic very low-density lipoprotein (HTG-VLDL). This receptor is crucial for the uptake of chylomicrons, HTG-VLDL, and trypsinized VLDL lacking apoE in macrophages. APOB48R may contribute necessary lipids, lipid-soluble vitamins, and other nutrients to reticuloendothelial cells. Elevated plasma triglyceride levels may cause APOB48R to be a factor in foam cell formation, endothelial dysfunction, and atherothrombogenesis (PMID: 10852956; 9633939; 15591219).

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