Anticorps Polyclonal de lapin anti-APOBEC1

APOBEC1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32857-1-PBS

Synonymes

APO1, APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, Apolipoprotein B mRNA-editing enzyme catalytic subunit 1, C->U-editing enzyme APOBEC-1

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Galerie de données de validation

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  WB analysis using 32857-1-AP (same clone as 32857-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32857-1-AP (APOBEC1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32857-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32857-1-PBS cible APOBEC1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: APOBEC1 Protéine recombinante Ag26715
• Nom complet: apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: NM_001304566
• Symbole du gène: APOBEC1
• Identification du gène (NCBI): 339
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Apolipoprotein B mRNA-editing enzyme catalytic subunit 1 (APOBEC1) is a member of the cytidine deaminase enzyme family. It forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP) (PMID: 30844405). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs (PMID: 24916387; 11727199). APOBEC1 plays a crucial role in RNA editing, which is essential for the proper function of these proteins. Additionally, APOBEC1 has been implicated in various cellular processes, including the regulation of gene expression and the maintenance of genomic stability (PMID: 33094286).

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