Anticorps Polyclonal de lapin anti-APOBEC3A

APOBEC3A Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25084-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 25084-1-AP (same clone as 25084-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25084-1-AP (APOBEC3A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25084-1-PBS in a different storage buffer formulation.

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  IF Staining of THP-1 using 25084-1-AP (same clone as 25084-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using APOBEC3A antibody (25084-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 25084-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25084-1-PBS cible APOBEC3A dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: APOBEC3A Protéine recombinante Ag18845
• Nom complet: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
• Masse moléculaire calculée: 199 aa, 23 kDa
• Poids moléculaire observé: 23 kDa
• Numéro d’acquisition GenBank: BC126416
• Symbole du gène: APOBEC3A
• Identification du gène (NCBI): 200315
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

APOBEC3A, also known as A3A, belongs to the cytidine and deoxycytidylate deaminase family. APOBEC3A plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. APOBEC3A is expressed in several cell types, including keratinocytes and myeloid cells (PMID: 28825669). APOBEC3A has 2 isoforms with the molecular mass of 22 and 23 kDa.

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