Anticorps Polyclonal de lapin anti-APPBP2

APPBP2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12409-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 12409-1-AP (same clone as 12409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12409-1-AP (APPBP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12409-1-AP (same clone as 12409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12409-1-AP (APPBP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12409-1-PBS cible APPBP2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: APPBP2 Protéine recombinante Ag3092
• Nom complet: amyloid beta precursor protein (cytoplasmic tail) binding protein 2
• Masse moléculaire calculée: 585 aa, 67 kDa
• Poids moléculaire observé: 67 kDa
• Numéro d’acquisition GenBank: BC018121
• Symbole du gène: APPBP2
• Identification du gène (NCBI): 10513
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Amyloid proteinbinding protein 2 (APPBP2) is a hydrophilic tubulin that interacts with microtubules and is functionally involved in beta-amyloid precursor protein (APP) transport and/or processing. Based on the regulation of microtubules and APP, APPBP2 is found to be involved in the oncogenesis of various types of cancers, such as breast cancer, ovarian clear cell adenocarcinomas, desmoplastic medulloblastomas and neuroblastomas. Recently, Studies have demonstrated that APPBP2 is a potential target for diagnosis and therapeutic intervention in non-small cell lung cancer (NSCLC) (PMID: 31105033).

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