Anticorps Recombinant de lapin anti-AQP6

AQP6 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240175F9

N° de cat : 83322-3-PBS

Synonymes

Aquaporin6, Aquaporin 6, AQP 6, 240175F9

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Galerie de données de validation

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  WB analysis using 83322-3-RR (same clone as 83322-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83322-3-RR (AQP6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83322-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83322-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83322-3-RR against Human AQP6 were performed. The affinity constant is 0.749 nM.

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Informations sur le produit

83322-3-PBS cible AQP6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: AQP6 Protéine recombinante Ag26845
• Nom complet: aquaporin 6, kidney specific
• Masse moléculaire calculée: 29 kDa
• Poids moléculaire observé: 34 kDa
• Numéro d’acquisition GenBank: NM_001652
• Symbole du gène: AQP6
• Identification du gène (NCBI): 363
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AQP6 (Aquaporin-6) has recently been identified as an intracellular vesicle water channel with anion permeability that is activated by low pH or HgCl2 (PMID: 12034750). It could be involved in physiological mechanisms of fluid movement, acid-base regulation, and/or anion transport. The calculated MW of AQP6 is 29 kDa, but the actual observed MW is around 35 kDa, which represents glycosylated AQP6 monomer forms (PMID: 19811639).

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