Anticorps Polyclonal de lapin anti-ARAP3

ARAP3 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22578-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 22578-1-AP (same clone as 22578-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 22578-1-AP (same clone as 22578-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22578-1-AP (ARAP3 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22578-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22578-1-PBS cible ARAP3 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ARAP3 Protéine recombinante Ag17436
• Nom complet: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
• Masse moléculaire calculée: 1544 aa, 170 kDa
• Numéro d’acquisition GenBank: BC009968
• Symbole du gène: ARAP3
• Identification du gène (NCBI): 64411
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ARAP3 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3) is unique for its dual specificity GAPs (GTPase activating protein) activity for Arf6 (ADP-ribosylation factor 6) and RhoA (Ras homolog gene family member A) regulated by PtdIns(3,4,5)P3 (phosphatidylinositol (3,4,5)-trisphosphate) and a small GTPase Rap1-GTP and is involved in regulation of cell shape and adhesion.

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