- Phare
- Validé par KD/KO
Anticorps Monoclonal anti-Arginase-1
Arginase-1 Monoclonal Antibody for IF/ICC
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain, porc, rat, souris
Applications
IF/ICC
Conjugaison
CoraLite®594 Fluorescent Dye
CloneNo.
5D6D12
N° de cat : CL594-66129
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en IF/ICC | cellules HepG2, | 
Dilution recommandée
| Application | Dilution | 
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| IF | See 5 publications below | 
Informations sur le produit
CL594-66129 cible Arginase-1 dans les applications de IF/ICC et montre une réactivité avec des échantillons Humain, porc, rat, souris
| Réactivité | Humain, porc, rat, souris | 
| Réactivité citée | Humain, souris | 
| Hôte / Isotype | Mouse / IgG1 | 
| Clonalité | Monoclonal | 
| Type | Anticorps | 
| Immunogène | Arginase-1 Protéine recombinante Ag8810 | 
| Nom complet | arginase, liver | 
| Masse moléculaire calculée | 236aa,25 kDa; 322aa,35 kDa | 
| Numéro d’acquisition GenBank | BC005321 | 
| Symbole du gène | Arginase-1 | 
| Identification du gène (NCBI) | 383 | 
| Conjugaison | CoraLite®594 Fluorescent Dye | 
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm | 
| Forme | Liquide | 
| Méthode de purification | Purification par protéine G | 
| Tampon de stockage | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA | 
| Conditions de stockage | Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. | 
Informations générales
Arginase-1 (Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406). ARG1 is a novel biomarker of post-stroke immune suppression(2016). The antibody is conjugated with CL594, Ex/Em 593 nm/614 nm.
Protocole
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 Arginase-1 antibody CL594-66129 | Download protocol | 
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols | 
Publications
| Species | Application | Title | 
|---|---|---|
| Adv Sci (Weinh) Wireless Localized Electrical Stimulation Generated by an Ultrasound-Driven Piezoelectric Discharge Regulates Proinflammatory Macrophage Polarization. | ||
| ACS Nano Biomimetic Trypsin-Responsive Structure-Bridged Mesoporous Organosilica Nanomedicine for Precise Treatment of Acute Pancreatitis | ||
| Adv Sci (Weinh) ROS-Driven Nanoventilator for MRSA-Induced Acute Lung Injury Treatment via In Situ Oxygen Supply, Anti-Inflammation and Immunomodulation | ||
| Adv Sci (Weinh) Natural Enzyme-Loaded Polymeric Stealth Coating-Armed Engineered Probiotics by Disrupting Tumor Lactate Homeostasis to Synergistic Metabolism-Immuno-Enzyme Dynamic Therapy | ||
| Adv Sci (Weinh) Mitochondria-Targeted ROS Scavenging Natural Enzyme Cascade Nanogels for Periodontitis Treatment via Hypoxia Alleviation and Immunomodulation | 
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
| FH Rachel (Verified Customer) (08-09-2022) | This ab works really well for IF in murine liver samples (formalin-fixed). 
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