Anticorps Polyclonal de lapin anti-ARHGAP10

• Phare
• Validé par KD/KO

ARHGAP10 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55139-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse heart using 55139-1-AP (same clone as 55139-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

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  WB analysis of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse kidney using 55139-1-AP (same clone as 55139-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 55139-1-AP (same clone as 55139-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 55139-1-AP (ARHGAP10 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 55139-1-AP (ARHGAP10 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

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Informations sur le produit

55139-1-PBS cible ARHGAP10 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: Rho GTPase activating protein 10
• Masse moléculaire calculée: 89 kDa
• Poids moléculaire observé: 89 kDa
• Numéro d’acquisition GenBank: NM_024605
• Symbole du gène: ARHGAP10
• Identification du gène (NCBI): 79658
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARHGAP10, also named as GRAF2, is GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. It is essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. ARHGAP10 inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. It stabilizes PAK-2p34 thereby increasing stimulation of cell death. The antibody is specific to ARHGAP10.

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