• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Anticorps Polyclonal de lapin anti-ARHGAP24

ARHGAP24 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

canin, Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18834-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Immunohistochemistry (IHC) staining of human kidney tissue using ARHGAP24 Polyclonal antibody (18834-1-AP)

    IHC staining of human kidney using 18834-1-AP (same clone as 18834-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 18834-1-AP (ARHGAP24 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 18834-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using ARHGAP24 Polyclonal antibody (18834-1-AP)

    IHC staining of human kidney using 18834-1-AP (same clone as 18834-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 18834-1-AP (ARHGAP24 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 18834-1-PBS in a different storage buffer formulation.

Informations sur le produit

18834-1-PBS cible ARHGAP24 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons canin, Humain, rat, souris

Réactivité canin, Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Peptide
Nom complet Rho GTPase activating protein 24
Masse moléculaire calculée 84 kDa
Poids moléculaire observé 73 kDa
Numéro d’acquisition GenBankBC098580
Symbole du gène ARHGAP24
Identification du gène (NCBI) 83478
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARHGAP24, also named as FILGAP, is involved in cell polarity, cell morphology and cytoskeletal organization. ARHGAP24 acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. ARHGAP24 controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. ARHGAP24 can suppress the activity of RAC1 and CDC42 in vitro. Its overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis. The antibody may recognize all the isoforms of ARHGAP24 except isoform 5.

{{ptg:RelatedPrimaryAntibodies}}