Anticorps Polyclonal de lapin anti-ARHGAP5

ARHGAP5 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55165-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 55165-1-AP (same clone as 55165-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55165-1-AP (ARHGAP5 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55165-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 55165-1-AP (same clone as 55165-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 55165-1-AP (ARHGAP5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55165-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

55165-1-PBS cible ARHGAP5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: Rho GTPase activating protein 5
• Masse moléculaire calculée: 172 kDa
• Poids moléculaire observé: 170-190 kDa
• Numéro d’acquisition GenBank: NM_001173
• Symbole du gène: ARHGAP5
• Identification du gène (NCBI): 394
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARHGAP5, also named as RHOGAP5 and p190-B, is GTPase-activating protein for Rho family members. It may play a role in the reduction of the p21rasGTPase-activating potential of p120GAP. ARHGAP5 can be directly phosphorylated on a single identified tyrosine residue by the activated INS and IGF-1 receptors. It also has been shown to be tyrosine phosphorylated by cSrc and vSrc. Additionally the GAP domain of ARHGAP5 is shown to attenuate signal transducing activity of Rac, Rho and CDC42. The antibody is specific to ARHGAP5.

{{ptg:RelatedPrimaryAntibodies}}