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Anticorps Polyclonal de lapin anti-ARHGEF11

ARHGEF11 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30508-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using ARHGEF11 Polyclonal antibody (30508-1-AP)

    WB analysis using 30508-1-AP (same clone as 30508-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30508-1-AP (ARHGEF11 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30508-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse colon tissue using ARHGEF11 Polyclonal antibody (30508-1-AP)

    IHC staining of mouse colon using 30508-1-AP (same clone as 30508-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 30508-1-AP (ARHGEF11 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30508-1-PBS in a different storage buffer formulation.

Informations sur le produit

30508-1-PBS cible ARHGEF11 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène ARHGEF11 Protéine recombinante Ag33104
Nom complet Rho guanine nucleotide exchange factor (GEF) 11
Masse moléculaire calculée168 kDa
Poids moléculaire observé200-220 kDa
Symbole du gène ARHGEF11
Identification du gène (NCBI) 9826
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARHGEF11 (Rho guanine nucleotide exchange factor 11) is a specific guanine nucleotide exchange factor (GEF) for RhoA, which is a critical regulator of actin cytoskeleton dynamics and organization of dendritic spines and inhibitor of spine maintenance (PMID: 28036092). ARHGEF11 has been proven to promote tumor metastasis in glioblastoma and ovarian carcinoma (PMID: 33122451).

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