Anticorps Polyclonal de lapin anti-ARHGEF4

• Phare
• Validé par KD/KO

ARHGEF4 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55213-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse brain using 55213-1-AP (same clone as 55213-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55213-1-AP (ARHGEF4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  WB analysis of multi-cells/tissue using 55213-1-AP (same clone as 55213-1-PBS)

  WB result of 55213-1-AP (ARHGEF4 Antibody). This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 55213-1-AP (same clone as 55213-1-PBS)

  IP result of anti-ARHGEF4 (IP:55213-1-AP, 4ug; Detection:55213-1-AP 1:1000) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 55213-1-AP (same clone as 55213-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 55213-1-AP (ARHGEF4 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 55213-1-AP (same clone as 55213-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 55213-1-AP (ARHGEF4 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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Informations sur le produit

55213-1-PBS cible ARHGEF4 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: Rho guanine nucleotide exchange factor (GEF) 4
• Masse moléculaire calculée: 79 kDa
• Poids moléculaire observé: 72 kDa
• Numéro d’acquisition GenBank: NM_015320
• Symbole du gène: ARHGEF4
• Identification du gène (NCBI): 50649
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARHGEF4, also named as KIAA1112 and Asef, acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC, ARHGEF4 may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion.(PMID: 10873612). This antibody is specific to ARHGEF4.

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