Anticorps Recombinant de lapin anti-ARMC4

ARMC4 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241122G4

N° de cat : 84004-3-PBS

Synonymes

RP11 691I13.1, Outer dynein arm-docking complex subunit 2, ODAD2, Armadillo repeat-containing protein 4, armadillo repeat containing 4

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Galerie de données de validation

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  WB analysis of mouse testis using 84004-3-RR (same clone as 84004-3-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 84004-3-RR (ARMC4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84004-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84004-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84004-3-RR against Human ARMC4 were performed. The affinity constant is 1.29 nM.

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Informations sur le produit

84004-3-PBS cible ARMC4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ARMC4 Protéine recombinante Ag22340
• Nom complet: armadillo repeat containing 4
• Masse moléculaire calculée: 1044 aa, 116 kDa
• Poids moléculaire observé: 116 kDa
• Numéro d’acquisition GenBank: BC140846
• Symbole du gène: ODAD2
• Identification du gène (NCBI): 55130
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ODAD2 contains ten Armadillo repeat motifs (ARMs) and one HEAT repeat, and is thought to be involved in ciliary and flagellar movement. This protein has been shown to localize to the ciliary axonemes and at the ciliary base of respiratory cells. Studies indicate that mutations in this gene cause partial outer dynein arm (ODA) defects in respiratory cilia. The cilia of cells with mutations in this gene displayed either reduced ciliary beat frequency and amplitude, or, complete immotility. Some individuals with primary ciliary dyskensia (PCD) have been shown to have mutations in this gene. PCD is characterized by chronic airway disease and left/right body asymmetry defects.

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