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Anticorps Recombinant de lapin anti-ARMC9

ARMC9 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242346G7

N° de cat : 84724-4-PBS

Synonymes

242346G7

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using ARMC9 Recombinant antibody (84724-4-RR)

    WB analysis using 84724-4-RR (same clone as 84724-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84724-4-RR (ARMC9 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84724-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84724-4-RR

    Affinity and Kinetic Characterization of 84724-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84724-4-RR against Human ARMC9 were performed. The affinity constant is 0.459 nM.

Informations sur le produit

84724-4-PBS cible ARMC9 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène ARMC9 Protéine recombinante Ag27511
Nom complet armadillo repeat containing 9
Masse moléculaire calculée 817 aa, 92 kDa
Poids moléculaire observé 75 kDa
Numéro d’acquisition GenBankBC004514
Symbole du gène ARMC9
Identification du gène (NCBI) 80210
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARMC9 (Armadillo Repeat Containing 9) belongs to the ARMC subfamily characterized by a class of tandem repeat proteins with a length of approximately 42 amino acids (PMID: 34912852). ARMC9 localizes to centrioles and the proximal portion of the cilium in mammalian cilia (PMID: 32453716). The variants of ARMC9 lead to Joubert syndrome (JBTS), a recessive neurodevelopmental ciliopathy characterized by characterized by hypotonia, ataxia, abnormal eye movements, and variable cognitive impairment(PMID: 28625504; PMID: 32453716). ARMC9 has two isoforms with molecular weights of 92 kDa and 76 kDa.

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