Anticorps Monoclonal anti-ARPC1B

ARPC1B Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2C8A1

N° de cat : 67320-1-PBS

Synonymes

ARC41, Arp2/3 complex 41 kDa subunit, ARPC1B, p40 ARC, p41 ARC

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Galerie de données de validation

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  WB analysis using 67320-1-Ig (same clone as 67320-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67320-1-Ig (ARPC1B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67320-1-PBS in a different storage buffer formulation.

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  IHC staining of human appendicitis using 67320-1-Ig (same clone as 67320-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human appendicitis tissue slide using 67320-1-Ig (ARPC1B antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67320-1-PBS in a different storage buffer formulation.

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  IHC staining of human appendicitis using 67320-1-Ig (same clone as 67320-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human appendicitis tissue slide using 67320-1-Ig (ARPC1B antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67320-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse spleen using 67320-1-Ig (same clone as 67320-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 67320-1-Ig (ARPC1B antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67320-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67320-1-PBS cible ARPC1B dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: ARPC1B Protéine recombinante Ag29095
• Nom complet: actin related protein 2/3 complex, subunit 1B, 41kDa
• Masse moléculaire calculée: 41 kDa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC007555
• Symbole du gène: ARPC1B
• Identification du gène (NCBI): 10095
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARPC1B also known as ARC41, p41-ARC, or p40-ARC, is one of seven subunits of the human Arp2/3 protein complex, that belongs to the SOP2 family. ARPC1B localizes on centrosomes and has a distinct role in centrosomal homeostasis. ARPC1B is both a physiological activator and substrate of Aurora A kinase, and these interactions help to maintain mitotic integrity in mammalian cells. In recent resaeach, ARPC1B is selected as a candidate prediction marker for sensitivity of Choroidal malignant melanomas to radiotherapy.

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