Anticorps Polyclonal de lapin anti-ARRDC1

ARRDC1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21030-1-PBS

Synonymes

Alpha-arrestin 1, arrestin domain containing 1, Arrestin domain-containing protein 1

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Galerie de données de validation

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  WB analysis using 21030-1-AP (same clone as 21030-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21030-1-AP (ARRDC1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21030-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 21030-1-AP (same clone as 21030-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 21030-1-AP (ARRDC1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21030-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 21030-1-AP (same clone as 21030-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 21030-1-AP (ARRDC1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21030-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21030-1-PBS cible ARRDC1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ARRDC1 Protéine recombinante Ag15341
• Nom complet: arrestin domain containing 1
• Masse moléculaire calculée: 433 aa, 46 kDa
• Poids moléculaire observé: 46-50 kDa
• Numéro d’acquisition GenBank: BC032346
• Symbole du gène: ARRDC1
• Identification du gène (NCBI): 92714
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ARRDC1, or Arrestin-Domain Containing Protein 1, is a protein that plays a significant role in the formation and release of extracellular vesicles, specifically a subtype known as ARMMs (Arrestin-Domain Containing Protein 1-mediated microvesicles). ARRDC1 is localized to the cytosolic side of the plasma membrane and recruits the ESCRT-I complex protein TSG101 to initiate outward membrane budding. This protein is also involved in the regulation of protein cargo and release of extracellular vesicles, including both exosomes and ectosomes. The absence of ARRDC1 can lead to changes in the protein cargo within these vesicles, indicating its importance in the sorting and packaging process.

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