Anticorps Polyclonal de lapin anti-ASCL1

ASCL1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23751-1-PBS

Synonymes

Achaete-scute homolog 1, ASH1, ASH-1, bHLHa46, Class A basic helix-loop-helix protein 46

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Galerie de données de validation

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  WB analysis using 23751-1-AP (same clone as 23751-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23751-1-AP (ASCL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23751-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 23751-1-AP (same clone as 23751-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23751-1-AP (ASCL1 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23751-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23751-1-PBS cible ASCL1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ASCL1 Protéine recombinante Ag19360
• Nom complet: achaete-scute complex homolog 1 (Drosophila)
• Masse moléculaire calculée: 25 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: BC003134
• Symbole du gène: ASCL1
• Identification du gène (NCBI): 429
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

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