Anticorps Recombinant de lapin anti-ASIC1

ASIC1 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242749B11

N° de cat : 85089-1-PBS

Synonymes

ACCN2, 242749B11, Acid-sensing ion channel 1, Amiloride-sensitive cation channel 2, neuronal, ASIC

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Galerie de données de validation

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  WB analysis using 85089-1-RR (same clone as 85089-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85089-1-RR (ASIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85089-1-PBS in a different storage buffer formulation.

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  WB analysis using 85089-1-RR (same clone as 85089-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85089-1-RR (ASIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85089-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01789-2

  Cytometric bead array standard curve of MP01789-2, ASIC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85089-1-PBS. Detection antibody: 85089-2-PBS. Standard: Ag25941. Range: 0.313-40 ng/mL.

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  Cytometric bead array standard curve of MP01789-1

  Cytometric bead array standard curve of MP01789-1, ASIC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85089-1-PBS. Detection antibody: 85089-3-PBS. Standard: Ag25941. Range: 0.313-40 ng/mL.

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Informations sur le produit

85089-1-PBS cible ASIC1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ASIC1 Protéine recombinante Ag25941
• Nom complet: amiloride-sensitive cation channel 2, neuronal
• Masse moléculaire calculée: 60 kDa
• Poids moléculaire observé: 60-70 kDa
• Numéro d’acquisition GenBank: NM_001095
• Symbole du gène: ASIC1
• Identification du gène (NCBI): 41
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ASIC1(Acid-sensing ion channel 1), also named as ACCN2, BNaC2 or amiloride-sensitive cation channel 2, is a member of the ASICs family. ASICs, an H+-gated subgroup of the epithelial Na+ channel/degenerin (ENaC/DEG) superfamily, are widely expressed throughout the central and peripheral nervous system and triggered by increased extracellular acidification (PMID: 28518134, 27941930). ASIC1 is a key player in acidosis-induced tumor growth and invasiveness. Clinically, alterations of ASIC1 are associated with poor survival in breast cancer (PMID: 26686084).

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