Anticorps Polyclonal de lapin anti-ASXL1

ASXL1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16803-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 16803-1-AP (same clone as 16803-1-PBS)

  Various lysates were subjected to Tris-acetate gel system followed by western blot with 16803-1-AP (ASXL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16803-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16803-1-PBS cible ASXL1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ASXL1 Protéine recombinante Ag10290
• Nom complet: additional sex combs like 1 (Drosophila)
• Masse moléculaire calculée: 84aa,10 kDa; 1541aa,165 kDa
• Poids moléculaire observé: ~200 kDa
• Numéro d’acquisition GenBank: BC064984
• Symbole du gène: ASXL1
• Identification du gène (NCBI): 171023
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Additional sex combs-like 1 (ASXL1) is a member of the ASXL family, which is involved in epigenetic regulation. It is one of the mammalian Asx homologs. Mutations in the ASXL1 gene are frequently found in myeloid neoplasms, breast cancers and prostate cancers (PMID: 30013160; PMID: 22436456; PMID: 26470845). In patients with myeloid malignancies, ASXL1 mutations are mostly heterozygous frameshift or nonsense mutations that result in C-terminal truncation (PMID: 30982744; PMID: 26095772; PMID: 32683582; PMID: 29643185).

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