Anticorps Polyclonal de lapin anti-ATP6V0D2

ATP6V0D2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33364-1-PBS

Synonymes

ATP6, ATP6D2, V-ATPase subunit d 2, VMA6, V-type proton ATPase subunit d 2

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Galerie de données de validation

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  WB analysis using 33364-1-AP (same clone as 33364-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33364-1-AP (ATP6V0D2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33364-1-PBS in a different storage buffer formulation.

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Informations sur le produit

33364-1-PBS cible ATP6V0D2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ATP6V0D2 Protéine recombinante Ag38739
• Nom complet: ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
• Masse moléculaire calculée: 40 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC065207
• Symbole du gène: ATP6V0D2
• Identification du gène (NCBI): 245972
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ATP6V0D2 is a subunit of the vacuolar proton-translocating ATPase (V-ATPase) complex, which is responsible for acidifying intracellular compartments and the extracellular environment. This protein is crucial for maintaining the acidic environment necessary for various cellular processes, including bone resorption by osteoclasts (PMID: 19113919). ATP6V0D2 is also involved in the regulation of tumor-associated macrophages, where it influences tumor progression through the lactate/ATP6V0D2/HIF-2α axis (PMID: 30431439).

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