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Anticorps Polyclonal de lapin anti-AVEN

AVEN Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25846-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of MCF-7 cells using AVEN Polyclonal antibody (25846-1-AP)

    WB analysis of MCF-7 using 25846-1-AP (same clone as 25846-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 25846-1-AP (AVEN Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25846-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of K-562 cells using AVEN Polyclonal antibody (25846-1-AP)

    WB analysis of K-562 using 25846-1-AP (same clone as 25846-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 25846-1-AP (AVEN Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25846-1-PBS in a different storage buffer formulation.

Informations sur le produit

25846-1-PBS cible AVEN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène AVEN Protéine recombinante Ag23020
Nom complet apoptosis, caspase activation inhibitor
Masse moléculaire calculée 39 kDa
Poids moléculaire observé 50 kDa
Numéro d’acquisition GenBankBC010488
Symbole du gène AVEN
Identification du gène (NCBI) 57099
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AVEN (Apoptosis caspase activation inhibitor) is known to play a role in male and female germ cell development. AVEN protein has also been shown to inhibit the mitochondrial apoptosis pathway by binding to and inhibiting the self-association of proapoptotic APAF-1, as well as binding to and enhancing antiapoptotic BCL-xL activity. AVEN has also recently been shown to function as an activator of the cell cycle-regulating ATM kinase in the DNA damage response pathway. Molecular weight of this protein detected by WB is 50 kDa (PMID: 22751129).

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