Anticorps Polyclonal de lapin anti-Antizyme inhibitor 1

Antizyme inhibitor 1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(13)

N° de cat : 11548-1-AP

Synonymes

AZIN1, OAZIN, OAZI, AZIN 1, AZI1

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Galerie de données de validation

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  WB analysis using 11548-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 11548-1-AP (Antizyme inhibitor 1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules A549, cellules HepG2, cellules NCI-H1299, cellules PC-3

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 10 publications below
• IHC: See 5 publications below
• IF: See 2 publications below

Informations sur le produit

11548-1-AP cible Antizyme inhibitor 1 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Antizyme inhibitor 1 Protéine recombinante Ag2082
• Nom complet: antizyme inhibitor 1
• Masse moléculaire calculée: 49.5 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC019279
• Symbole du gène: AZIN1
• Identification du gène (NCBI): 51582
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

AZIN1(Antizyme inhibitor 1) is also named as OAZI, OAZIN and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis, and playing a role in the regulation of polyamine synthesis (negative regulator of cellular polyamines).

Publications

Species	Application	Title
human	WB	Cancer Cell; The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.; Authors - Leng Han
human	WB	J Clin Invest; Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.; Authors - Anna Bianchi-Smiraglia
human	WB,IHC,IF	J Exp Clin Cancer Res; AZIN1 level is increased in medulloblastoma and correlates with c-Myc activity and tumor phenotype; Authors - Julie Sesen
human	WB	Mol Ther; Targeting RNA Editing of Antizyme Inhibitor 1: a Potential Oligonucleotide-Based Antisense Therapy for Cancer.; Authors - Daryl Jin Tai Tay
rat	WB	Theranostics; Crucial Role of miR-433 in Regulating Cardiac Fibrosis.; Authors - Lichan Tao
mouse	WB,IHC	Kidney Int; The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway.; Authors - Li Rong R

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