Anticorps Polyclonal de lapin anti-Amylin

Amylin Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22305-1-PBS

Synonymes

IAPP, DAP, Diabetes associated peptide, Diabetes-associated peptide, islet amyloid polypeptide

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Galerie de données de validation

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  IHC staining of human pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 22305-1-AP (Amylin Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 22305-1-AP (Amylin Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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  IHC staining of rat pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22305-1-PBS cible Amylin dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: islet amyloid polypeptide
• Masse moléculaire calculée: 10 kDa
• Numéro d’acquisition GenBank: NM_000415
• Symbole du gène: Amylin
• Identification du gène (NCBI): 3375
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring a tumor of the pancreas that is derived from beta cells and secretes INS. IAPP is co-secreted with INS by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

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