Anticorps Recombinant de lapin anti-Angiopoietin-like 3/ANGPTL3

Angiopoietin-like 3/ANGPTL3 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

230498F11

N° de cat : 83165-3-RR

Synonymes

angiopoietin like 3, Angptl3, hypl

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Galerie de données de validation

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  WB analysis using 83165-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83165-3-RR (Angiopoietin-like 3/ANGPTL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  WB analysis of A375 using 83165-3-RR

  A375 cells were subjected to SDS PAGE followed by western blot with 83165-3-RR (Angiopoietin-like 3/ANGPTL3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HepG2, cellules A375, cellules HEK-293

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

83165-3-RR cible Angiopoietin-like 3/ANGPTL3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: angiopoietin-like 3
• Masse moléculaire calculée: 53KD
• Poids moléculaire observé: 54 kDa, 70 kDa
• Numéro d’acquisition GenBank: NM_013913.4
• Symbole du gène: Angptl3
• Identification du gène (NCBI): 30924
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

ANGPTL3 belongs to the angiopoietin-like protein family. ANGPTL3 is mainly synthesized by liver cells and is notably expressed in kidney podocytes. Accumulating evidences have revealed that ANGPTL3 plays a critical role in both biological processes, such as lipid metabolism, angiogenesis and haematopoietic function and pathological changes, including atherosclerosis, carcinogenesis, nephrotic syndrome, diabetes, liver diseases and so on. Thus, ANGPTL3 may serve as a potential biomarker in these diseases. ANGPTL3 belongs to a multifunctional secreted protein that mainly expresses in the liver, and is regulated by numerous post-translational modifications, including multiple cleavage and glycosylation (PMID: 30615486).

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