Anticorps Recombinant de lapin anti-Angiotensinogen/AGT

Angiotensinogen/AGT Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250570F8

N° de cat : 86134-1-PBS

Synonymes

Agt, Serpina8

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Galerie de données de validation

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  WB analysis using 86134-1-RR (same clone as 86134-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86134-1-RR (Agt antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86134-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 86134-1-RR (same clone as 86134-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86134-1-RR (Agt antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86134-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86134-1-PBS cible Angiotensinogen/AGT dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Angiotensinogen/AGT Protéine recombinante Eg2763
• Nom complet: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 52-55 kDa
• Numéro d’acquisition GenBank: N/A
• Symbole du gène: Agt
• Identification du gène (NCBI): 11606
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

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