Anticorps Monoclonal anti-Apolipoprotein A II/APOA2

Apolipoprotein A II/APOA2 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1G1A2

N° de cat : 66773-1-PBS

Synonymes

APOA2, apolipoprotein A II, ApoA-II, Apo-AII, ApoA II

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Galerie de données de validation

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  WB analysis of human plasma using 66773-1-Ig (same clone as 66773-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66773-1-Ig (Apolipoprotein A II/APOA2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66773-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66773-1-Ig (same clone as 66773-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66773-1-Ig (Apolipoprotein A II/APOA2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66773-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 66773-1-Ig (same clone as 66773-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66773-1-Ig (Apolipoprotein A II antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66773-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66773-1-PBS cible Apolipoprotein A II/APOA2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Apolipoprotein A II/APOA2 Protéine recombinante Ag9863
• Nom complet: apolipoprotein A-II
• Masse moléculaire calculée: 100 aa, 11 kDa
• Poids moléculaire observé: 8-11 kDa
• Numéro d’acquisition GenBank: BC005282
• Symbole du gène: APOA2
• Identification du gène (NCBI): 336
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Apolipoprotein A-II (APOA2) is a major component of high density lipoprotein (HDL) and it plays an important role in directing the fate of lipid metabolism among HDL. It is primarily synthesized by liver. The predicted MW of ApoA2 is 11 kDa, while the mature form is smaller (7-10 kDa) since the signal peptide was cleaved. In humans, most of circulating apoA2 exist as dimer. Five types of APOA2 dimer exist: homodimer apoA2-ATQ/ATQ, heterodimer apoA2-ATQ/AT, homodimer apoA2-AT/AT, apoA2-AT/A, and apoA2-A/A. ApoA2 isoforms are considered to be some of the most promising serum/plasma biomarkers for aiding the early detection of pancreatic cancer. (PMID: 29081441, 29481802)

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