Anticorps Polyclonal de lapin anti-Aquaporin 4

• Phare
• Validé par KD/KO

Aquaporin 4 Polyclonal Antibody for IF-P

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, IF-P

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

Publications(4)

Avis (2)

N° de cat : CL647-16473

Synonymes

AQP 4, AQP4, aquaporin 4, HMIWC2, MIWC, WCH4

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Galerie de données de validation

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  IF Staining of mouse brain using CL647-16473

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 647 Aquaporin 4 antibody (CL647-16473) at dilution of 1:200.

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Applications testées

• Résultats positifs en IF-P: tissu cérébral de souris,

Dilution recommandée

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• IHC: See 1 publications below
• IF: See 3 publications below

Informations sur le produit

CL647-16473 cible Aquaporin 4 dans les applications de IHC, IF-P et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Aquaporin 4 Protéine recombinante Ag9561
• Nom complet: Aquaporin 4
• Masse moléculaire calculée: 323 aa, 35 kDa
• Poids moléculaire observé: 35-37 kDa, 32-34 kDa
• Numéro d’acquisition GenBank: BC022286
• Symbole du gène: Aquaporin 4
• Identification du gène (NCBI): 361
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Conditions de stockage: Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Aquaporins are specialized water transport channels in plasma membranes of water-permeable tissues. Aquaporin-4 (AQP4) is the most abundant water channel in the human central nervous system and is important to fluid movements in brain. Aquaporin-4 exists as two isoforms, a long (M1) isoform with translation initiation at Met-1, and a shorter (M23) isoform with translation initiation at Met-23, with molecular weights around 35-37 kDa and 32-34 kDa, respectively.

Publications

Species	Application	Title
mouse	IF	Adv Mater; Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment; Authors - Yuewen Zhai
	IHC	Front Neurosci; Stress in utero: prenatal dexamethasone exposure causes greater structural gliovascular alterations in female offspring than in males; Authors - Magda Ferreira-Rodrigues
mouse	IF	J Clin Invest; APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading; Authors - Chanung Wang
mouse	IF	Cell Rep; Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease; Authors - Min Yu

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

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FH

Aito (Verified Customer) (05-27-2025)

Aquaporin 4 and DAPI in a slide of human glioblastoma sample.

• Applications: Immunofluorescence
• Primary Antibody Dilution: 1/100
• Cell Tissue Type: human brain glioblastoma

CL Plus 647 Aquaporin 4 Antibody Immunofluorescence validation (1/100 dilution) in human brain glioblastoma (Cat no:CL647-16473)

FH

Vanessa (Verified Customer) (09-27-2023)

Works Perfectly!

• Applications: Immunohistochemistry, Immunofluorescence
• Primary Antibody Dilution: 1:200
• Cell Tissue Type: Brain

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