Anticorps Recombinant de lapin anti-Beta Arrestin 1

Beta Arrestin 1 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240974C3

N° de cat : 83837-1-PBS

Synonymes

ARRB1, 240974C3, ARB 1, ARB1, ARB2

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Galerie de données de validation

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  WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83837-1-RR (Beta Arrestin 1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83837-1-RR (Arrestin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 83837-1-RR (same clone as 83837-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 83837-1-RR (Arrestin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83837-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00811-2

  Cytometric bead array standard curve of MP00811-2, Beta Arrestin 1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83837-2-PBS. Detection antibody: 83837-1-PBS. Standard: Ag7608. Range: 0.625-80 ng/mL.

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  Affinity and Kinetic Characterization of 83837-1-PBS

  Biolayer interferometry (BLl) kinetic assay of 83837-1-PBS against Human Beta Arrestin 1 was performed. The affinity constant is 1.40 nM.

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  Affinity and Kinetic Characterization of 83837-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83837-1-RR against Human Beta Arrestin 1 were performed. The affinity constant is 0.759 nM.

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Informations sur le produit

83837-1-PBS cible Beta Arrestin 1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Beta Arrestin 1 Protéine recombinante Ag7608
• Nom complet: arrestin, beta 1
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 47-55 kDa
• Numéro d’acquisition GenBank: BC003636
• Symbole du gène: Beta Arrestin 1
• Identification du gène (NCBI): 408
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).

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