Anticorps Monoclonal anti-B7-H3/CD276

B7-H3/CD276 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG1, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

MJ18

N° de cat : 65221-1-PBS

Synonymes

Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3

---

Galerie de données de validation

• 

  FC experiment of mouse peritoneal macrophages using 65221-1-Ig (same clone as 65221-1-PBS)

  1X10^6 mouse peritoneal macrophages were surface stained with 1 ug Anti-Mouse CD276 (65221-1-Ig, Clone:MJ18) and FITC anti-rat IgG1 Antibody at dilution 1:100 (red), or unstained (blue). Cells were not fixed. This data was developed using the same antibody clone with 65221-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

65221-1-PBS cible B7-H3/CD276 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Mouse IgG2a Fc-CD276 (aa 1-242) fusion protein
• Nom complet: CD276 antigen
• Numéro d’acquisition GenBank: BC019436
• Symbole du gène: Cd276
• Identification du gène (NCBI): 102657
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).

{{ptg:RelatedPrimaryAntibodies}}