Anticorps Recombinant de lapin anti-B7-H3/CD276

B7-H3/CD276 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

230305A10

N° de cat : Biotin-FcA98017

Synonymes

CD276, 230305A10, 4Ig-B7-H3, B7 H3, B7 homolog 3

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Galerie de données de validation

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  FC experiment of human monocyte-derived dendritic using Biotin-FcA98017

  1x10^6 human monocyte-derived dendritic cells were surface stained with 0.25 ug Biotin Anti-Human B7-H3/CD276 Rabbit RecAb (Biotin-FcA98017, Clone: 230305A10) (red) or 0.25 ug FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9), and PE-conjugated streptavidin. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules dendritiques dérivées de monocytes humains,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-FcA98017 cible B7-H3/CD276 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: B7-H3/CD276 Protéine recombinante Eg0075
• Nom complet: CD276 molecule
• Masse moléculaire calculée: 57 kDa
• Numéro d’acquisition GenBank: NM_001024736
• Symbole du gène: CD276
• Identification du gène (NCBI): 80381
• Conjugaison: Biotin
• Excitation/Emission maxima wavelengths: -
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).

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