Anticorps Recombinant de lapin anti-B7-H3/CD276

B7-H3/CD276 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

230305A10

N° de cat : CL594-98017

Synonymes

CD276, B7-H3, B7H3, B7 homolog 3, B7 H3

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Galerie de données de validation

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  FC experiment of human monocyte-derived immature dendritic cells using CL594-98017

  1x10^6 human monocyte-derived immature dendritic cells were surface stained with 5 ul CoraLite®594 Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody (CL594-98017, Clone:230305A10) (red), or Isotype Control (blue). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human monocyte-derived immature dendritic cells

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98017 cible B7-H3/CD276 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD276 molecule
• Masse moléculaire calculée: 57 kDa
• Numéro d’acquisition GenBank: NM_001024736
• Symbole du gène: CD276
• Identification du gène (NCBI): 80381
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).

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