Anticorps Recombinant de lapin anti-B7-H4

B7-H4 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243033D6

N° de cat : 82850-6-PBS

Synonymes

VTCN1, B7 H4, B7 homolog 4, B7h.5, B7H4

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Galerie de données de validation

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  WB analysis of SK-BR-3 using 82850-6-RR (same clone as 82850-6-PBS)

  SK-BR-3 cells were subjected to SDS PAGE followed by western blot with 82850-6-RR (VTCN1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82850-6-PBS in a different storage buffer formulation.

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Informations sur le produit

82850-6-PBS cible B7-H4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: B7-H4 Protéine recombinante Eg0098
• Nom complet: V-set domain containing T cell activation inhibitor 1
• Masse moléculaire calculée: 282 aa, 31 kDa
• Poids moléculaire observé: 65 kDa
• Numéro d’acquisition GenBank: NM_024626
• Symbole du gène: B7-H4
• Identification du gène (NCBI): 79679
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

B7-H4, also named VTCN1, B7X, or B7S1, is a single-pass type I membrane protein, which contains two immunoglobulin-like domains and belongs to the immunoglobulin superfamily. B7-H4 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. B7-H4 is over-expressed in many cancers, including breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The predicted molecular weight of B7‑H4 is 31 kDa. The glycosylated B7‑H4 is 50 to 80 kDa, and the non-glycosylated form is 28 kDa.

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