Anticorps Polyclonal de lapin anti-B7-H6

• Phare
• Validé par KD/KO

B7-H6 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27428-1-PBS

Synonymes

B7H6, NCR3LG1, B7 H6, B7 homolog 6, Natural cytotoxicity triggering receptor 3 ligand 1

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Galerie de données de validation

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  WB analysis of HEK-293 using 27428-1-AP (same clone as 27428-1-PBS)

  WB result of B7-H6 antibody (27428-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-B7-H6 transfected HEK-293 cells. This data was developed using the same antibody clone with 27428-1-PBS in a different storage buffer formulation.

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  WB analysis using 27428-1-AP (same clone as 27428-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27428-1-AP (B7H6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27428-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27428-1-PBS cible B7-H6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: B7-H6 Protéine recombinante Ag26532
• Nom complet: hypothetical protein DKFZp686O24166
• Masse moléculaire calculée: 51 kDa
• Poids moléculaire observé: 75-80 kDa
• Numéro d’acquisition GenBank: BC136800
• Symbole du gène: B7H6
• Identification du gène (NCBI): 374383
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

B7-H6, also known as NCR3LG1, is a member of the B7 family of immunoreceptors. It is a 454-aa-long type I transmembrane protein consisting of an extracellular region, a transmembrane segment, and a cytoplasmic domain which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), an SH2-binding domain, and an SH3-binding motif. B7-H6 triggers NKp30-mediated activation of human NK cells (PMID: 19528259). It has been reported that B7H6 is expressed in various types of tumor cells and plays a prominent role in natural killer cell immunosurveillance (PMID: 35697295). The apparent molecular weight of B7-H6 is larger than the calculated molecular weight of 51 kDa due to glycosylation (PMID: 19528259).

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