Anticorps Recombinant de lapin anti-BAFF

BAFF Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242006E4

N° de cat : 84541-3-PBS

Synonymes

242006E4

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Galerie de données de validation

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  WB analysis using 84541-3-RR (same clone as 84541-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84541-3-RR (BAFF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84541-3-PBS in a different storage buffer formulation.

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  WB analysis of U-937 using 84541-3-RR (same clone as 84541-3-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 84541-3-RR (BAFF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84541-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84541-3-PBS cible BAFF dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FusionProtein
• Nom complet: tumor necrosis factor (ligand) superfamily, member 13b
• Masse moléculaire calculée: 34kd
• Poids moléculaire observé: 32kd, 17kd
• Numéro d’acquisition GenBank: NM_033622
• Symbole du gène: Tnfsf13b
• Identification du gène (NCBI): 24099
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BAFF (B-cell-activating factor), also called Tnfsf13b (Tumor necrosis factor ligand superfamily member 13B) and CD257, is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in stimulating B- and T-cell function and the regulation of humoral immunity. A third B-cell-specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response (PMID: 12867412). BAFF cleaved into 2 chains: membrane form is 32-35 kDa; soluble form is 17 kDa.

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