Anticorps Polyclonal de lapin anti-BAG1L-specific

BAG1L-specific Polyclonal Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16148-1-PBS

Synonymes

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Galerie de données de validation

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  IF Staining of HepG2 using 16148-1-AP (same clone as 16148-1-PBS)

  Immunofluorescent analysis of HepG2 cells, using BAG1 antibody 16148-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 16148-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16148-1-PBS cible BAG1L-specific dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: BCL2-associated athanogene
• Masse moléculaire calculée: 39 kDa
• Numéro d’acquisition GenBank: NM_004323
• Symbole du gène: BAG1
• Identification du gène (NCBI): 573
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BAG1 has been identified that modulates gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M, and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S(p33) is not clear yet. This antibody can recognize BAG1L and BAG1V.

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