Anticorps Monoclonal anti-BAG3

BAG3 Monoclonal Antibody for WB, IF/ICC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

4G6C2

N° de cat : 68076-1-PBS

Synonymes

4G6C2, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, BIS

---

Galerie de données de validation

• 

  WB analysis using 68076-1-Ig (same clone as 68076-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68076-1-Ig (BAG3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68076-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68076-1-Ig (same clone as 68076-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68076-1-Ig (BAG3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68076-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68076-1-Ig (same clone as 68076-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68076-1-Ig (BAG3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68076-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 68076-1-Ig (same clone as 68076-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HepG2 cells using BAG3 antibody (68076-1-Ig, Clone: 4G6C2 ) at dilution of 1:1000 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68076-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

68076-1-PBS cible BAG3 dans les applications de WB, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: BAG3 Protéine recombinante Ag17608
• Nom complet: BCL2-associated athanogene 3
• Masse moléculaire calculée: 61 kDa
• Poids moléculaire observé: 74 kDa
• Numéro d’acquisition GenBank: BC006418
• Symbole du gène: BAG3
• Identification du gène (NCBI): 9531
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BAG3 (Bcl2-associated athanogene 3) belongs to the BAG protein family, the co-chaperone that binds to Hsc70/Hsp70 through the BAG domain and modulates their activity in polypeptide folding. BAG3 contains also a WW domain and a proline-rich (PXXP) repeat, that mediate binding to partners different from Hsp70. Through interacting with different molecular partner, BAG3 influences several cell processes, such as apoptosis, autophagy and cell motility. BAG3 protein has been reported to sustain cell survival, resistance to therapy, and/or motility and metastatization in several tumor types, thus being identified as a potential target for anticancer therapies. In addition, defects in BAG3 are the cause of some myopathy.

{{ptg:RelatedPrimaryAntibodies}}