Anticorps Recombinant de lapin anti-BAK

BAK Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242458D10

N° de cat : 85200-1-PBS

Synonymes

BAK1, 242458D10, Bcl-2 homologous antagonist/killer, Bcl2-L-7, Bcl-2-like protein 7

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Galerie de données de validation

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  WB analysis using 85200-1-RR (same clone as 85200-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85200-1-RR (BAK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85200-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85200-1-PBS cible BAK dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: BCL2-antagonist/killer 1
• Masse moléculaire calculée: 23 kDa
• Poids moléculaire observé: 23-25 kDa
• Numéro d’acquisition GenBank: BC004431
• Symbole du gène: BAK1
• Identification du gène (NCBI): 578
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The BAK encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

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