Anticorps Polyclonal de lapin anti-BBS10

• Phare
• Validé par KD/KO

BBS10 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12421-2-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of HepG2 using 12421-2-AP (same clone as 12421-2-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 12421-2-AP (BBS10 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12421-2-PBS in a different storage buffer formulation.

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  WB analysis of A549 using 12421-2-AP (same clone as 12421-2-PBS)

  A549 cells were subjected to SDS PAGE followed by western blot with 12421-2-AP (BBS10 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12421-2-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 12421-2-AP (same clone as 12421-2-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 12421-2-AP (BBS10 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12421-2-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 cells using 12421-2-AP (same clone as 12421-2-PBS)

  IF result (nuclear and the base of cilia stain) of anti-BBS10 (12421-2-AP; 1:50) with hTERT-RPE1 cell (PFA fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 12421-2-PBS in a different storage buffer formulation.

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Informations sur le produit

12421-2-PBS cible BBS10 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BBS10 Protéine recombinante Ag3073
• Nom complet: Bardet-Biedl syndrome 10
• Masse moléculaire calculée: 81 kDa
• Poids moléculaire observé: 81 kDa
• Numéro d’acquisition GenBank: BC013795
• Symbole du gène: BBS10
• Identification du gène (NCBI): 79738
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BBS10, also named as C12orf58, belongs to the TCP-1 chaperonin family. It is probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex, BBS10 may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation. (PMID:20080638,19190184) Defects in BBS10 are the cause of Bardet-Biedl syndrome type 10 (BBS10).

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