Anticorps Polyclonal de lapin anti-BBS6

BBS6 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13078-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13078-1-AP (BBS6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 13078-1-AP (same clone as 13078-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 13078-1-AP (BBS6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 cells using 13078-1-AP (same clone as 13078-1-PBS)

  IF result (cytoplasm and the base of cilia stain) of anti-BBS6 (13078-1-AP; 1:50) with hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13078-1-PBS cible BBS6 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BBS6 Protéine recombinante Ag3785
• Nom complet: McKusick-Kaufman syndrome
• Masse moléculaire calculée: 62 kDa
• Poids moléculaire observé: 63 kDa
• Numéro d’acquisition GenBank: BC028973
• Symbole du gène: MKKS
• Identification du gène (NCBI): 8195
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

MKKS also known as BBS6 is a probable chaperone given to the amino acid similarity to the chaperonin family of proteins and may play a role in protein processing in limb, cardiac and reproductive system development. The mutations in BBS6 have been linked to Bardet-Biedl syndrome (BBS) which is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. It may also get involved in cellular organization processes, in particular relating to ciliary/flagellar and centrosomal activities.

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