Anticorps Recombinant de lapin anti-BCAM

BCAM Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250778C11

N° de cat : 98521-3-RR

Synonymes

Auberger B antigen, Basal cell adhesion molecule, B-CAM cell surface glycoprotein, CD239, F8/G253 antigen

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Galerie de données de validation

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  FC experiment of Human peripheral blood erythrocytes using 98521-3-RR

  1x10^6 human peripheral blood erythrocytes were surface stained with 0.25 ug Anti-Human BCAM Rabbit RecAb (98521-3-RR, Clone: 250778C11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of Human peripheral blood erythrocytes using 98521-3-RR

  1x10^6 human peripheral blood erythrocytes were surface stained with 0.25 ug Anti-Human BCAM Rabbit RecAb (98521-3-RR, Clone: 250778C11) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood erythrocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98521-3-RR cible BCAM dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: BCAM Protéine recombinante Eg2567
• Nom complet: basal cell adhesion molecule (Lutheran blood group)
• Masse moléculaire calculée: 67 kDa
• Numéro d’acquisition GenBank: BC050450
• Symbole du gène: BCAM
• Identification du gène (NCBI): 4059
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Basal cell adhesion molecule (Lu/BCAM) is a membrane-bound glycoprotein of the immunoglobulin superfamily (IgSF), functioning as a receptor for the extracellular matrix protein, laminin. BCAM (Lutheran/basal cell-adhesion molecule, a glycoprotein) belongs to the immunoglobulin superfamily which contains both Lu blood group and BCAM tumor-associated antigens. Proteomics analysis suggests that BCAM might be a potential biomarker for pancreatic cancer (PMID: 19199705). BCAM, involved in cell adhesion and migration, can also promote tumor metastasis and has been elucidated to play a functional role in the metastasis of thyroid cancer and gastric cancer (PMID: 10728810, 35941663).

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