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Anticorps Polyclonal de lapin anti-BEX1/2

BEX1/2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12390-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of human brain tissue using BEX1/2 Polyclonal antibody (12390-1-AP)

    WB analysis of human brain using 12390-1-AP (same clone as 12390-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 12390-1-AP (BEX1/2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12390-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human medulloblastoma tissue using BEX1/2 Polyclonal antibody (12390-1-AP)

    IHC staining of human medulloblastoma using 12390-1-AP (same clone as 12390-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human medulloblastoma using 12390-1-AP (BEX1/2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12390-1-PBS in a different storage buffer formulation.

Informations sur le produit

12390-1-PBS cible BEX1/2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène BEX1/2 Protéine recombinante Ag3066
Nom complet brain expressed X-linked 2
Masse moléculaire calculée 128 aa, 15 kDa
Poids moléculaire observé 10-15 kDa
Numéro d’acquisition GenBankBC015522
Symbole du gène BEX2
Identification du gène (NCBI) 84707
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BEX1 is a signaling adapter molecule involved in p75NTR/NGFR signaling. It lays a role in cell cycle progression and neuronal differentiation. BEX1 inhibits neuronal differentiation in response to nerve growth factor (NGF). BEX2 is a regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. It regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.

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