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Anticorps Polyclonal de lapin anti-BICD2

BICD2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29603-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using BICD2 Polyclonal antibody (29603-1-AP)

    WB analysis using 29603-1-AP (same clone as 29603-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29603-1-AP (BICD2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29603-1-PBS in a different storage buffer formulation.

Informations sur le produit

29603-1-PBS cible BICD2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène BICD2 Protéine recombinante Ag31279
Nom complet bicaudal D homolog 2 (Drosophila)
Masse moléculaire calculée 855 aa, 97 kDa
Poids moléculaire observé93-96 kDa
Numéro d’acquisition GenBankBC073970
Symbole du gène BICD2
Identification du gène (NCBI) 23299
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Protein bicaudal D homolog 2 (BICD2) acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623).

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