Anticorps Monoclonal anti-BIK

BIK Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

1B1C10

N° de cat : 68438-1-PBS

Synonymes

Apoptosis inducer NBK, BIK, BIP1, BP4, NBK

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Galerie de données de validation

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  WB analysis using 68438-1-Ig (same clone as 68438-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68438-1-Ig (BIK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68438-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68438-1-PBS cible BIK dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: BIK Protéine recombinante Ag6353
• Nom complet: BCL2-interacting killer (apoptosis-inducing)
• Masse moléculaire calculée: 18 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC001599
• Symbole du gène: BIK
• Identification du gène (NCBI): 638
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

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